Article
Targeted treatments for vascular malformations: current state of the art.
Journal of thrombosis and haemostasis : JTH - 1 Nov 2024
Seront Emmanuel, Hermans Cedric, Boon Laurence M, Vikkula Miikka
Abstract excerpt
Vascular malformations, which arise from anomalies in angiogenesis, encompass capillary, lymphatic, venous, arteriovenous, and mixed malformations, each affecting specific vessel types. Historically, therapeutic options such as sclerotherapy and surgery have shown limited efficacy in complicated malformations. Most vascular malformations stem from hereditary or somatic mutations akin to oncogenic alterations,...
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