Article
New and Emerging Targeted Therapies for Vascular Malformations.
American journal of clinical dermatology - 1 Oct 2020
Van Damme An, Seront Emmanuel, Dekeuleneer Valérie, Boon Laurence M, Vikkula Miikka
Abstract excerpt
Vascular malformations are inborn errors of vascular morphogenesis and consist of localized networks of abnormal blood and/or lymphatic vessels with weak endothelial cell proliferation. They have historically been managed by surgery and sclerotherapy. Extensive insight into the genetic origin and molecular mechanism of development has been accumulated over the last 20 years. Since the discovery of the first...
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