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Article

Metabolic phenotypes of doxorubicin-induced cardiotoxicity among patients with breast cancer.

Metabolomics : Official journal of the Metabolomic Society - 4 Jul 2026

Singh Amarnath, Jun Se-Ran, Wallis Katherine, S Lan Renny, Todorova Valentina, Joseph Su L, Makhoul Sam, Hsu Ping-Ching

Abstract excerpt

BACKGROUND: Doxorubicin (DOX)-based chemotherapy has improved survival outcomes in breast cancer patients but is often limited by doxorubicin-induced cardiotoxicity (DIC). Currently, no validated biomarkers can predict early DIC. Identifying novel biomarkers is essential for detecting patients at higher risk and enable timely interventions before irreversible cardiac injury occurs. METHODS: Twenty-seven breast...

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PMID: 42400748
DOI: 10.1007/s11306-026-02469-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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