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Article

Impact of race on mutational profile and survival in acute myeloid leukemia: a single-institution experience (2014-2024).

Annals of hematology - 2 Jul 2026

Joshi Utsav, Zahra Fatima Tuz, Patel Pujan, Al Ali Najla, Thompson Zachary, Pakasticali Nagehan, Song Jinming, Agrawal Vishakha, Shallis Rory, Xie Zhuoer, Yun Seongseok, Kuykendall Andrew, Padron Eric, Walker Alison, Sallman David, Komrokji Rami, Lancet Jeffrey, Hussaini Mohammad, Chan Onyee

Abstract excerpt

Acute myeloid leukemia (AML) is a biologically heterogeneous hematologic malignancy, and racial disparities in outcomes remain incompletely characterized. This retrospective study analyzed 677 patients diagnosed with AML at Moffitt Cancer Center (2014-2024) to evaluate the impact of race on genomic profiles and clinical outcomes. The cohort comprised 18.6% Black, 19.1% Hispanic, and 62.3% White patients. While...

Read the complete abstract on PubMed

Topics

Adult
Aged
Female
Humans
Male

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Middle Aged

Black or African American

Hispanic or Latino

Isocitrate Dehydrogenase

Leukemia, Myeloid, Acute

Mutation

Proto-Oncogene Proteins p21(ras)

Retrospective Studies

Survival Rate

White

Source

Open in PubMed Open full text

Identifiers

PMID: 42393270
DOI: 10.1007/s00277-026-07145-3
PMCID: PMC13597553

Genes

ELN
TP53
IDH2
IDH1
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

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