A Distinct Immune Signature Characterizes Cirrhosis in Ethiopian Individuals With Chronic HBV Infection.

doi:10.1111/apt.70816

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Article

A Distinct Immune Signature Characterizes Cirrhosis in Ethiopian Individuals With Chronic HBV Infection.

Alimentary pharmacology & therapeutics - 1 Oct 2026

MacLeod Julia, Gudissa Fikadu G, Jeylan Asiya, Berhe Nega, Desalegn Hailemichael, Rossvoll Lasse, Johannessen Asgeir, Björkström Niklas K, Reikvam Dag Henrik, Niehrs Annika

Abstract excerpt

BACKGROUND AND AIMS: The immune cell phenotype of African patients living with chronic hepatitis B virus (HBV) infection is rarely described, despite high infection rates. This study investigated the differences in immune cell phenotypes in four distinct clinical phases of disease in an Ethiopian cohort. METHODS: Two hundred eighty-seven patients with untreated HBV infection, and no human immunodeficiency virus...

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Topics

Humans
Hepatitis B, Chronic
Male
Female
Liver Cirrhosis
Ethiopia

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Adult

Middle Aged

Flow Cytometry

Immunophenotyping

Killer Cells, Natural

Phenotype

Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 42387268
DOI: 10.1111/apt.70816
PMCID: PMC13559501

Genes

CD38
CD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Oct 2026.

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