Article
Evaluation of line-probe assay for molecular analysis and drug susceptibility of extra-pulmonary tuberculosis.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease - 1 Sept 2018
Raghuvanshi S, Kotwal A, Maheshwari R, Sindhwani G
Abstract excerpt
SETTING: Most epidemiological studies on Mycobacterium tuberculosis focus on pulmonary tuberculosis (TB), whereas extra-pulmonary TB (EPTB) remains poorly explored. OBJECTIVE: To study the rate of resistant EPTB cases among individuals with suspected EPTB using a commercial line-probe assay (LPA), polymerase chain reaction (PCR) and reverse hybridisation test. We also examined the molecular profile of the EPTB...
Topics
- Antitubercular Agents
- Bacteriological Techniques
- Cross-Sectional Studies
- Drug Resistance, Bacterial
- Early Diagnosis
- Genotype
- Humans
- India
- Isoniazid
- Microbial Sensitivity Tests
- Mycobacterium tuberculosis
- Polymerase Chain Reaction
- Rifampin