Article
Line probe assay for detection of rifampicin and isoniazid resistant tuberculosis in Pakistan.
JPMA. The Journal of the Pakistan Medical Association - 1 Aug 2012
Farooqi Joveria Qais, Khan Erum, Alam Syed Muhammed Zaheer, Ali Asho, Hasan Zahra, Hasan Rumina
Abstract excerpt
OBJECTIVE: To assess the efficacy of a line-probe assay delta (LiPA) as rapid diagnostic test for early detection of drug-resistant tuberculosis compared to conventional susceptibility methods in Pakistan. METHODS: Resistance to rifampicin (RIF) and isoniazid (INH) in 108 smear-positive pulmonary tuberculosis samples was detected using a line-probe assay [GenoType MTBDRplus (Hain Lifescience, GmbH, Nehren,...
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