Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Congenital hypoganglionosis: phenotype-based outcomes and evolution of diagnosis and management-a systematic review.

Pediatric surgery international - 29 Jun 2026

Nakamura Hiroki, Yamakawa Hiroshi, Aoki Nozomi, Tanaka Rina, Yoshimoto Sakiko, Okunobo Tokiko, Satake Ryosuke, Puri Prem, Doi Takashi

Abstract excerpt

PURPOSE: Congenital hypoganglionosis (CH) is a rare enteric neuropathy characterized by reduced and small ganglion cells in the myenteric plexus. We aimed to systematically review the clinical outcomes and diagnostic evolution of CH in children. METHODS: A systematic review was conducted in accordance with PRISMA guidelines using PubMed and Web of Science (1978-2025). Of 396 identified records, 32 studies...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hirschsprung Disease
Share to Infant, Newborn

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Phenotype

Source

Identifiers

PMID: 42370961
DOI: 10.1007/s00383-026-06504-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Congenital hypoganglionosis: phenotype-based outcomes and evolution of diagnosis and management-a systematic review.PMID 42370961Read ↗

Genotype-phenotype correlation and management of Megacystis-Microcolon-Intestinal Hypoperistalsis Syndrome: a descriptive cohort study.Semantic proximity Read ↗

Megacystis-Megacolon-Intestinal Hypoperistalsis Syndrome with Intestinal Neuronal Dysplasia: Expanding the Phenotypic Spectrum.Semantic proximity Read ↗

Novel classification and pathogenetic analysis of hypoganglionosis and adult-onset Hirschsprung's disease.Semantic proximity Read ↗

Management of Congenital Pouch Colon: Surgical Outcomes and Long-Term Follow-UpSemantic proximity Read ↗

Congenital Myasthenic Syndromes in 2018.Semantic proximity Read ↗

Enteric Neuromyopathies: Highlights on Genetic Mechanisms Underlying Chronic Intestinal Pseudo-ObstructionSemantic proximity Read ↗

Gastrointestinal and feeding difficulties in CHARGE syndrome: A review from head-to-toe.Semantic proximity Read ↗

Ischemia promotes hypertrophic nerve trunk formation and enteric neuron cell death in Hirschsprung’s diseaseSemantic proximity Read ↗

Lack of mucosal cholinergic innervation is associated with increased risk of enterocolitis in Hirschsprung’s diseaseSemantic proximity Read ↗

Variants in ACTG2 underlie a substantial number of Australasian patients with primary chronic intestinal pseudo-obstruction.Semantic proximity Read ↗

Diagnosis and Staging of Necrotizing Enterocolitis: Current Controversies and a Phenotype-Based FrameworkSemantic proximity Read ↗

Hirschsprung's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.