Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Novel classification and pathogenetic analysis of hypoganglionosis and adult-onset Hirschsprung's disease.

Digestive diseases and sciences - 1 Jun 2011

Do Mi Young, Myung Seung-Jae, Park Hyo-Jin, Chung Jun-Won, Kim In-Wha, Lee Sun Mi, Yu Chang Sik, Lee Hye Kyung, Lee Jong-Keuk, Park Young Soo, Jang Se Jin, Kim Hye Jin, Ye Byong Duk, Byeon Jeong-Sik, Yang Suk-Kyun, Kim Jin-Ho

Abstract excerpt

BACKGROUND AND AIMS: Researchers have not clearly described the clinical and pathogenetic features of hypoganglionosis and adult-onset Hirschsprung's disease, which cause pseudo-obstruction or intractable constipation. We conducted this study to explore these features of hypoganglionosis and adult-onset Hirschsprung's disease in Korean patients. METHODS: We enrolled 24 patients pathologically confirmed as having...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hirschsprung Disease
Share to Adolescent

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation

Share to Polymorphism, Genetic

Share to Proto-Oncogene Proteins c-ret

Share to Young Adult

Source

Identifiers

PMID: 21222160
DOI: 10.1007/s10620-010-1522-9

Genes

RET
EDN3
EDNRB
SOX10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Novel classification and pathogenetic analysis of hypoganglionosis and adult-onset Hirschsprung's disease.PMID 21222160Read ↗

Hirschsprung Disease and Other Enteric DysganglionosesSemantic proximity Read ↗

Hirschsprung’s Disease—Recent Understanding of Embryonic Aspects, Etiopathogenesis and Future Treatment AvenuesSemantic proximity Read ↗

Comprehensive characterization of the genetic landscape of familial Hirschsprung's disease.Semantic proximity Read ↗

mRNA sequencing provides new insights into the pathogenesis of Hirschsprung's disease in miceSemantic proximity Read ↗

High incidence of EDNRB gene mutation in seven southern Chinese familial cases with Hirschsprung's disease.Semantic proximity Read ↗

A Scoring System to Predict the Severity of Hirschsprung Disease at Diagnosis and Its Correlation With Molecular Genetics.Semantic proximity Read ↗

Exome sequencing identified a novel pathogenic RET variant with high variable expressivity and incomplete penetrance in an extended pedigree with Hirschsprung diseaseSemantic proximity Read ↗

The developmental etiology and pathogenesis of Hirschsprung disease.Semantic proximity Read ↗

Congenital hypoganglionosis: phenotype-based outcomes and evolution of diagnosis and management-a systematic review.Semantic proximity Read ↗

The Emerging Genetic Landscape of Hirschsprung Disease and Its Potential Clinical ApplicationsSemantic proximity Read ↗

Highly recurrent RET mutations and novel mutations in genes of the receptor tyrosine kinase and endothelin receptor B pathways in Chinese patients with sporadic Hirschsprung disease.Semantic proximity Read ↗

Total colonic aganglionosis in Hirschsprung disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.