Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular dissection of CD28-associated cytokine signaling in early psoriasis.

Molecular biology reports - 27 Jun 2026

Ismael Shahad Basil, AlChalabi Rawaa, Shareef Saja Ali, Majid Jabir, AlObaidi Russul, Al-Obaidi Jameel R

Abstract excerpt

BACKGROUND: Psoriasis is a chronic immune-mediated skin disorder characterized by excessive keratinocyte proliferation and abnormal T-cell activation. Cluster of Differentiation 28 (CD28), a costimulatory protein, plays a crucial role in psoriasis pathophysiology by enhancing T-cell activation and promoting cytokine release. METHODS: A case-control study was involving 168 newly diagnosed psoriasis patients and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to CD28 Antigens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytokines

Share to Lymphocyte Activation

Share to Promoter Regions, Genetic

Share to Psoriasis

Share to Signal Transduction

Share to T-Lymphocytes

Source

Open in PubMed Open full text

Identifiers

PMID: 42363986
DOI: 10.1007/s11033-026-12175-1
PMCID: PMC13310195

Genes

CD28

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

Molecular dissection of CD28-associated cytokine signaling in early psoriasis.PMID 42363986Read ↗

Association between Psoriasis Disease and IFN-λ Gene Polymorphisms.Semantic proximity Read ↗

Insights into IL‐29: Emerging role in inflammatory autoimmune diseasesSemantic proximity Read ↗

Genetic variation at the CD28 locus and its impact on expansion of pro-inflammatory CD28 negative T cells in healthy individuals.Semantic proximity Read ↗

The Role of the CD28 Family Receptors in T-Cell ImmunomodulationSemantic proximity Read ↗

rs2013278 in the multiple immunological-trait susceptibility locus CD28 regulates the production of non-functional splicing isoformsSemantic proximity Read ↗

The CD28 family: a T-cell rheostat for therapeutic control of T-cell activationSemantic proximity Read ↗

The life (and death) of CD4+ CD28(null) T cells in inflammatory diseases.Semantic proximity Read ↗

The association between CD28 gene rs3116496 polymorphism and breast cancer risk in Chinese women.Semantic proximity Read ↗

The story of CD4+ CD28- T cells revisited: solved or still ongoing?Semantic proximity Read ↗

Cytokine gene polymorphisms in atopic dermatitis.Semantic proximity Read ↗

The non-coding RNA miR-17~92 is a central mediator of T cell activationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.