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Article

Enterovirus D68 VP1 and VP3 Determine Neurotropism in Human Spinal Cord Organoids.

Viruses - 28 May 2026

Packard Jessica E, Jones Jennifer E, Yovel Gal, Freeman Megan Culler

Abstract excerpt

Enterovirus D68 (EV-D68) is a non-polio enterovirus that can cause a polio-like paralysis condition, acute flaccid myelitis (AFM). EV-D68-associated AFM cases waned in the US after 2018, and the reasons for this are unknown. It has recently been demonstrated that EV-D68 containing point mutations in viral structural proteins VP1 and VP3 resulted in decreased paralysis in different neonatal mouse models. However,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42357629
DOI: 10.3390/v18060619
PMCID: PMC13307885

Genes

AFM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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Enterovirus D68 VP1 and VP3 Determine Neurotropism in Human Spinal Cord Organoids.PMID 42357629Read ↗

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