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Article

A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine.

Nature communications - 6 Jul 2020

Guo Yanjun, Rist Pamela M, Daghlas Iyas, Giulianini Franco, Kurth Tobias, Chasman Daniel I

Abstract excerpt

Blood pressure (BP) was inconsistently associated with migraine and the mechanisms of BP-lowering medications in migraine prophylaxis are unknown. Leveraging large-scale summary statistics for migraine (Ncases/Ncontrols = 59,674/316,078) and BP (N = 757,601), we find positive genetic correlations of migraine with diastolic BP (DBP, rg = 0.11, P = 3.56 × 10-06) and systolic BP (SBP, rg = 0.06, P = 0.01), but not...

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Identifiers

PMID: 32632093
DOI: 10.1038/s41467-020-17002-0
PMCID: PMC7338361

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