Article
Shared genetic risk between migraine and coronary artery disease: A genome-wide analysis of common variants.
PloS one - 1 Jan 2017
Winsvold Bendik S, Bettella Francesco, Witoelar Aree, Anttila Verneri, Gormley Padhraig, Kurth Tobias, Terwindt Gisela M, Freilinger Tobias M, Frei Oleksander, Shadrin Alexey, Wang Yunpeng, Dale Anders M, van den Maagdenberg Arn M J M, Chasman Daniel I, Nyholt Dale R, Palotie Aarno, Andreassen Ole A, Zwart John-Anker
Abstract excerpt
Migraine is a recurrent pain condition traditionally viewed as a neurovascular disorder, but little is known of its vascular basis. In epidemiological studies migraine is associated with an increased risk of cardiovascular disease, including coronary artery disease (CAD), suggesting shared pathogenic mechanisms. This study aimed to determine the genetic overlap between migraine and CAD, and to identify shared...
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