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Article

HNRNPC as a Novel Therapeutic Target for Ischemic Heart Disease: Evidence From Mendelian Randomization and Experimental Validation.

Journal of the American Heart Association - 7 Jul 2026

Ye Hongmei, Wang Xinyu, Meng Siyu, Song Xuchen, He Xu, Huang Lin, Zhang Xiaohong, Guo Jing

Abstract excerpt

BACKGROUND: Several studies have suggested that N6-methyladenosine (m6A) plays an essential role in cardiovascular disease, but the causality of m6A on ischemic heart disease (IHD) remains unknown. Therefore, this study investigated the potential relationship between m6A and IHD using a 2-sample Mendelian randomization method. METHODS: The publicly available genome-wide association study data for m6A-related...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 42333679
DOI: 10.1161/JAHA.125.046773
PMCID: PMC13477384

Genes

HNRNPC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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