Article
Association between CHRNA5 polymorphisms and Parkinson's disease in Northern Chinese Han population: a case-control study.
Annals of human biology - 1 Dec 2026
Xian Wenke, Sun Xiaohui, Wang Yue, Sun Xiaohui, Zhang Jing, Qin Kunpeng, Zhou Yuting, He Qiqing, Li Yaqing, Xie Anmu, Hou Binghui
Abstract excerpt
BACKGROUND: Parkinson's disease (PD) is a complex neurodegenerative disorder characterised by the progressive loss of dopaminergic neurons in the substantia nigra, resulting in motor symptoms such as bradykinesia, resting tremor, rigidity, and postural instability. AIM: This study investigated the association between two single nucleotide polymorphisms of the nicotinic choline receptors α5 (CHRNA5), and the...
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