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Article

Multiomics Integration Prioritizes ZFP36L1 as a Candidate Susceptibility Gene Associated With Inflammatory and Angiogenic Pathways in Diabetic Retinopathy.

Journal of diabetes research - 1 Jan 2026

Dong Ruiqing, Hui Xiaoli, Luo Chenwen, Chen Shengnan, Gao Ning, He Mingqian, Shi Bingyin, Qiang Wei

Abstract excerpt

BACKGROUND: Diabetic retinopathy (DR) is a prevalent microvascular complication of diabetes and a leading cause of blindness despite available therapies, underscoring the need for novel therapeutic targets. METHODS: Integrated multiomics analysis combining (1) exploratory single-cell RNA sequencing of rat retinal tissues (three DRs vs. two controls), (2) Mendelian randomization (MR) using whole-blood eQTL data...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42318941
DOI: 10.1155/jdr/4312504
PMCID: PMC13280981

Genes

ZFP36L1
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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