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Article

(Lack of) genetic diversity in immune genes predates glacial isolation in the North American mountain goat (Oreamnos americanus).

The Journal of heredity - 1 Jan 2000

Shafer Aaron B A, Fan Chia Wei, Côté Steeve D, Coltman David W

Abstract excerpt

The major histocompatibility complex (MHC) plays an important role in an organism's ability to respond to pathogens. Immunogenetic diversity is advantageous as it permits the recognition of more external antigens. For this reason, MHC and immune gene variation are considered a barometer for the genetic health of wild populations. Mountain goats (Oreamnos americanus) were previously shown to have little variation...

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PMID: 22268162
DOI: 10.1093/jhered/esr138

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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