Machine learning-driven identification of virulence determinants in Borrelia burgdorferi associated with human dissemination.

Abstract excerpt

Lyme disease, the most common tick-borne infectious disease in the United States, presents with highly variable clinical outcomes, ranging from localized erythema migrans to severe disseminated complications affecting the heart, joints, and nervous system. The bacterial determinants underlying this phenotypic variation remain largely unknown, limiting our ability to predict disease progression and optimize...

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