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Article

Behavioral Phenotyping for Down Syndrome in Mice.

Current protocols in mouse biology - 1 Sept 2020

Roper Randall J, Goodlett Charles R, Martínez de Lagrán María, Dierssen Mara

Abstract excerpt

Down syndrome (DS) is the most frequent genetic cause of intellectual disability, characterized by alterations in different behavioral symptom domains: neurodevelopment, motor behavior, and cognition. As mouse models have the potential to generate data regarding the neurological basis for the specific behavioral profile of DS, and may indicate pharmacological treatments with the potential to affect their...

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Identifiers

PMID: 32780566
DOI: 10.1002/cpmo.79
PMCID: PMC7552827

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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