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Article

Clinical phenotypes and mortality predictors in pediatric critical pertussis: A multinational study.

Journal of infection and public health - 1 Aug 2026

Alghounaim Mohammad, Shaheen Naila A, Aldaithan Abdulrahman, Awlad Thani Saif, Kazzaz Yasser, Alfraij Abdulla

Abstract excerpt

BACKGROUND: Critical pertussis carries high mortality, yet early risk stratification remains challenging. Although hyperleukocytosis and pulmonary hypertension (PHT) are linked to poor outcomes, the prognostic role of white blood cell (WBC) trajectories and optimal thresholds remains unclear. This study identified predictors of mortality and characterized WBC dynamics, and optimal WBC threshold for treatment in...

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Child
Child, Preschool
Hypertension, Pulmonary
Infant
Leukocyte Count

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 42296648
DOI: 10.1016/j.jiph.2026.103276

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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