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Genetic variants of thioredoxin interacting protein gene and their association with diabetic peripheral neuropathy in type 2 diabetes mellitus.

Gene - 5 Nov 2026

Zhang Qianqian, Li Hongmin, Zhao Yongcai, Liu Xiaonan, Sun Qianqian, Li Jing

Abstract excerpt

AIMS: To investigate the association between genetic variants of the thioredoxin interacting protein (TXNIP) gene and diabetic peripheral neuropathy (DPN) in patients with type 2 diabetes mellitus (T2DM). METHODS: A total of 239 T2DM patients (144 in the DPN group and 95 in the T2DM-only group) and 283 healthy controls (NC group) were enrolled. Polymorphisms of TXNIP gene loci (rs7211, rs7212, rs4755, and rs9245)...

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Identifiers

PMID: 42289227
DOI: 10.1016/j.gene.2026.150271

Genes

TXNIP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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