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Article

Association between MTHFR variant and diabetic neuropathy.

Pharmacological reports : PR - 1 Feb 2018

Kakavand Hamidi Armita, Radfar Mania, Amoli Mahsa M

Abstract excerpt

BACKGROUND: Methylene-tetrahydrofolate reductase (MTHFR) gene variant may play an important role in the pathophysiology of diabetes and its complications due to its influence on plasma homocysteine levels and also its effect on scavenging peroxynitrite radicals. Diabetic peripheral neuropathy (DPN) is one of the most common diabetic chronic complications. The aim of this study was to investigate the relationship...

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Source

Identifiers

PMID: 29222982
DOI: 10.1016/j.pharep.2017.04.017

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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