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Article

Per- and polyfluoroalkyl substances, vitamin D, and risk of preterm birth in a Canadian cohort.

Environmental research - 1 Sept 2026

Fisher Mandy, Owen James, Marro Leonora, Potter Beth, Weiler Hope A, England-Mason Gillian, Borghese Michael M, Walker Mark, Dodds Linda, Helewa Michael, Arbuckle Tye E, Lanphear Bruce, von Dadelszen Peter, Simpson Ashlyn, Little Julian, Ashley-Martin Jillian

Abstract excerpt

BACKGROUND: Vitamin D, which is essential for calcium and phosphorus homeostasis, may also influence immune regulation and offer protection against preterm birth (PTB). Per- and polyfluoroalkyl substances (PFAS) are associated with both increases and decreases in 25-hydroxyvitamin D (25OHD) concentrations and have been shown to compete for binding sites on the vitamin D receptor (VDR). We investigated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 42288278
DOI: 10.1016/j.envres.2026.124999

Genes

PFAS
VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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