Article
Association between vitamin D plasma concentrations and VDR gene variants and the risk of premature birth.
BMC pregnancy and childbirth - 31 Dec 2019
Dutra Letícia Veríssimo, Affonso-Kaufman Fernando Alves, Cafeo Fernanda Ramires, Kassai Milene Saori, Barbosa Caio Parente, Santos Figueiredo Francisco Winter, Suano-Souza Fabíola Isabel, Bianco Bianca
Abstract excerpt
BACKGROUND: Premature birth is the main cause of mortality in children under 1 year, and vitamin D deficiency during gestation is associated with prematurity. The effects of vitamin D are mediated by its receptor, which is encoded by the VDR gene. VDR variants-such as single nucleotide variation (SNV)-are associated with increased risk of prematurity, but there are conflicting results. We evaluated serum vitamin...
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