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Article

Performance of a targeted next generation sequencing assay for mycobacterial identification and drug resistance from sputum and isolates.

Journal of clinical microbiology - 8 Jul 2026

Kuss-Duerkop Sharon K, Godo Paul, DeCurtis Emily K, Pham Van, Abushanab Lorraine, Archuleta Valerie, Robertson Gregory T, Wang Yongbao, Khare Reeti

Abstract excerpt

Accurate identification and genotypic drug resistance prediction in mycobacteria are essential for early diagnosis and appropriate clinical management. Targeted next-generation sequencing (tNGS) detects multiple genetic targets and enables direct testing from primary specimens. We evaluated identification using the Deeplex Myc-TB assay for Mycobacterium tuberculosis complex (MTBC) and nontuberculous mycobacteria...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 42283516
DOI: 10.1128/jcm.00106-26
PMCID: PMC13343929

Genes

NTM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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