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Article

ABCG2 Contributes to Multidrug Resistance and Aggressive Phenotypes Associated with ERK Signaling in Gastric Cancer.

International journal of molecular sciences - 2 Jun 2026

Türksoy Terzioğlu Özlem, Terzioğlu Gökhan

Abstract excerpt

Multidrug resistance remains a major obstacle in gastric cancer therapy and is frequently associated with aggressive phenotypes. Although ABCG2 is a well-known drug efflux transporter, its functional contribution to paclitaxel (PTX) resistance and its relationship with ERK signaling in gastric cancer remain incompletely understood. In this study, PTX-resistant gastric cancer cell models were established through...

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Share to ATP Binding Cassette Transporter, Subfamily G, Member 2
Share to Cisplatin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42278563
DOI: 10.3390/ijms27115039
PMCID: PMC13256579

Genes

ABCG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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