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Article

The phosphoenolpyruvate phosphotransferase system regulates cell length and width through semi-independent pathways.

Molecular biology of the cell - 1 Aug 2026

Surber Jacob, Morgenstein Randy M

Abstract excerpt

It has been known for over 80 years that bacterial cell size is affected by growth conditions. Cells grown in a nutrient-rich medium are larger and wider than those grown in a nutrient-poor medium. Yet even after decades of research, it is still not fully known how metabolism and cell size are coregulated. In this work, we describe a new source of metabolic control over Escherichia coli cell size, the...

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PMID: 42275207
DOI: 10.1091/mbc.E26-03-0129
PMCID: PMC13426487

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