Article
Generation of Regulatory Dendritic Cells From Living Donor Liver Transplant Perfusates.
Transplantation - 1 Aug 2026
Busà Rosalia, Zahorchak Alan F, Macedo Camila, Mitsufuji Suguru, Metes Diana M, Badami Ester, Elinoff Beth D, Lakkis Fadi G, Humar Abhinav, Conaldi Pier Giulio, Thomson Angus W
Abstract excerpt
BACKGROUND: Safety and immunological activity of donor blood monocyte-derived regulatory dendritic cells (DCreg) generated ex vivo have been demonstrated recently in living donor liver transplantation. A potential alternative/additional source of DCreg precursors is the allograft perfusion fluid. Our goal was to establish the extent to which DCreg could be generated from CD14 + myeloid precursors in living donor...
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