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Article

Pre-operative MRI-Based Radiomics for Predicting Telomerase Reverse Transcriptase Promoter Mutation Status in Glioma Patients: A Systematic Review and Meta-analysis.

Neurosurgical review - 10 Jun 2026

Foodeh Tina, Korani Mohammad Amir, Teymourzadeh Mohammad, Hassanpour-Fard-Khor Majid, Abdollahi Zeynab, Hatami Bahareh, Payandeh Asma, Shojaeshafiei Farzaneh, Seyed Ebrahimi Seyedeh Mahdieh, Fayazbakhsh Fatemeh, Delshad Mahda, Khodadadi Sanaz, Karimi Shirin, Mortezaei Ali, Shahidi Ramin

Abstract excerpt

TERT promoter (TERTp) mutations shape glioma prognosis and therapy, yet tissue testing can be limited by sampling error and surgical inaccessibility. MRI-based radiomics offers a non-invasive alternative. This study aimed to quantify the diagnostic accuracy of pre-operative MRI radiomics for predicting TERTp status and compare radiomics-only, clinical-only, and combined models.We conducted a...

Read the complete abstract on PubMed

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42265510
DOI: 10.1007/s10143-026-04362-2

Genes

TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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