Article
Human controlled ovarian hyperstimulation outcome is a polygenic trait.
Pharmacogenetics - 1 May 2004
de Castro Francisco, Morón Francisco J, Montoro Luis, Galán José J, Hernández Dámaso Pérez, Padilla Elisa Sánchez-Casas, Ramírez-Lorca Reposo, Real Luis M, Ruiz Agustín
Abstract excerpt
This study aimed to evaluate the association between follicle-stimulating hormone (FSH) hormone efficacy and FSHR, CYP19, ESR1 and ESR2 genes using single nucleotide polymorphism analyses. One hundred and seventy women with conserved ovarian function undergoing controlled ovarian stimulation (COS) with daily exogenous recombinant FSH administration. Women were categorized as poor responders to FSH (three or less...
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