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Article

Cytogenomic landscape of adult Philadelphia chromosome-positive acute lymphoblastic leukemia in Malaysia.

Cancer genetics - 1 Sept 2026

Phan Chin Lee, Zakaria Zubaidah, Yegappan Subramanian, Khang Tsung Fei, Ng Ching Ching

Abstract excerpt

BACKGROUND: Philadelphia chromosome-positive acute lymphoblastic leukemia (-Ph+ ALL) is a high-risk leukemia often accompanied by additional genomic abnormalities beyond BCR::ABL1. METHODS: We analyzed 74 newly diagnosed adult -Ph+ ALL patients. Additional chromosomal abnormalities (ACAs) were assessed by conventional cytogenetics in 51 patients and copy number variations (CNVs) by combined array comparative...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 42247916
DOI: 10.1016/j.cancergen.2026.05.006

Genes

CDKN2A
IKZF1
PAX5
ABL1
BCR
RB1
VPREB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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