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Article

Prognostic implications of additional genomic lesions in adult Philadelphia chromosome-positive acute lymphoblastic leukemia.

Haematologica - 1 Feb 2019

Fedullo Anna Lucia, Messina Monica, Elia Loredana, Piciocchi Alfonso, Gianfelici Valentina, Lauretti Alessia, Soddu Stefano, Puzzolo Maria Cristina, Minotti Clara, Ferrara Felicetto, Martino Bruno, Chiusolo Patrizia, Calafiore Valeria, Paolini Stefania, Vignetti Marco, Vitale Antonella, Guarini Anna, Foà Robin, Chiaretti Sabina

Abstract excerpt

To shed light onto the molecular basis of Philadelphia chromosome-positive acute lymphoblastic leukemia and to investigate the prognostic role of additional genomic lesions, we analyzed copy number aberrations using the Cytoscan HD Array in 116 newly diagnosed adult patients with Philadelphia chromosome-positive acute lymphoblastic leukemia enrolled in four different GIMEMA protocols, all based on a...

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Identifiers

PMID: 30190342
DOI: 10.3324/haematol.2018.196055
PMCID: PMC6355475

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