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Article

Neurobehavioral Impacts of the Autism Risk Gene, WAC: Studies Involving C. elegans and Mice.

Molecular neurobiology - 5 Jun 2026

Boonpraman Napissara, Kim Da-Woon, Tislerics Elena, Barot Janki, Pacheco-Cruz Dariangelly, Kuhn Nathan C, Vogt Daniel, Sammi Shreesh Raj

Abstract excerpt

Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by a broad spectrum of behavioral impairments. While multiple genetic and environmental factors are attributed to its cause, biological underpinnings are still poorly understood. The WAC gene has been primarily linked with DeSanto-Shinawi syndrome, a rare neurodevelopmental disorder. Due to overlapping manifestations, studies on WAC...

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Source

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Identifiers

PMID: 42247028
DOI: 10.1007/s12035-026-05964-z
PMCID: PMC13241405

Genes

WAC
CHRNA7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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