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Article

Investigating autism associated genes in C. elegans reveals candidates with a role in social behaviour.

PloS one - 1 Jan 2021

Rawsthorne Helena, Calahorro Fernando, Holden-Dye Lindy, O' Connor Vincent, Dillon James

Abstract excerpt

Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterised by a triad of behavioural impairments and includes disruption in social behaviour. ASD has a clear genetic underpinning and hundreds of genes are implicated in its aetiology. However, how single penetrant genes disrupt activity of neural circuits which lead to affected behaviours is only beginning to be understood and less is known...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34043629
DOI: 10.1371/journal.pone.0243121
PMCID: PMC8158995

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