Article
Association between lipid metabolism and lung adenocarcinoma: Evidence from Mendelian randomization and tissue microbiome analysis.
Journal of cancer research and therapeutics - 1 May 2026
Chen Qianying, Xu Zhanyu, Zheng Tiaozhan, Pang Haiyan, He Zhiyi
Abstract excerpt
BACKGROUND: Tissue-resident microbiota play an important role in lung cancer development. This study aimed to characterize the microbiota profile associated with fatty acid metabolism and related genes and examine its effect on treatment outcomes in lung cancer. METHODS: Genome-wide association data on saturated fatty acid ratio, total cholesterol, and linoleic acid ratio were analyzed with lung adenocarcinoma as...
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