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Article

CAMK1D as a potential therapeutic target for gut microbiota-driven promotion of lung adenocarcinoma development.

PeerJ - 1 Jan 2026

Yan Nuo, Zhang Yang, Wang Silin, Hu Sheng, Ruan Liancheng, Wang Yunzhe, Feng Weiqiang, Xiong Wenxun, Zhang Wenxiong, Wei Yiping, Yao Chuan

Abstract excerpt

Background: The gut microbiome is closely associated with malignant tumors; however the specific mechanisms by which it contributes to the development of lung adenocarcinoma remain unclear. In this study, we performed a two-sample bidirectional Mendelian randomization (MR) analysis to assess the causal relationship between the gut microbiome and lung adenocarcinoma. By identifying single nucleotide polymorphism...

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Topics

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Share to Adenocarcinoma of Lung
Share to Gastrointestinal Microbiome

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to Genome-Wide Association Study

Share to Lung Neoplasms

Share to Mendelian Randomization Analysis

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 41868793
DOI: 10.7717/peerj.20985
PMCID: PMC13005612

Genes

CAMK1D
BCAS3
DNAH1
PDE10A
DNAI3
DOCK2
INSYN2B
MYO18B
SULT4A1
SUOX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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