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Application of a short amplicon triallelic SNP panel for parentage analysis of highly degraded DNA.

Forensic science international - 1 Oct 2026

Xie Mingkun, Zheng Feifei, Luo Jiao, Fu Xiaoyi, Wang Yuepeng, Liu Lian, Xie Qiheng, Li Jienan

Abstract excerpt

Genetic typing of highly degraded DNA remains one of the most critical challenges in forensic genetics, particularly in parentage analysis, where relationship assessment is needed despite limited genetic information. To address this, we developed and validated a high efficiency multiplex system comprising 25 triallelic single nucleotide polymorphisms (SNPs) specifically optimized for highly degraded DNA, with all...

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PMID: 42217939
DOI: 10.1016/j.forsciint.2026.113027

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