Article
Developing multiplexed SNP assays with special reference to degraded DNA templates.
Nature protocols - 1 Jan 2006
Sanchez Juan J, Endicott Phillip
Abstract excerpt
This protocol describes a single nucleotide polymorphism (SNP) genotyping strategy for highly degraded DNA, using a two-stage multiplex whereby multiple fragments are first amplified in a single exponential reaction and the products of this PCR are added to a linear single-base-extension reaction...
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