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Article

A three-groups non-local model for combining heterogeneous data sources to identify genes associated with Parkinson's disease.

Biometrics - 9 Apr 2026

Wixson Troy P, Shaby Benjamin A, Philtron Daisy L, Lima Leandro A, Wyman Stacia K, Kaye Julia A, Finkbeiner Steven

Abstract excerpt

We seek to identify genes involved in Parkinson's disease (PD) by combining information across different experiment types. Each experiment, taken individually, may contain too little information to distinguish some important genes from incidental ones. However, when experiments are combined using the proposed statistical framework, additional power emerges. The fundamental building block of the family of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42216962
DOI: 10.1093/biomtc/ujag090
PMCID: PMC13221837

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