An integrative network approach for longitudinal stratification in Parkinson's disease.

Abstract excerpt

Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor symptoms resulting from the loss of dopamine-producing neurons in the brain. Currently, there is no cure for the disease which is in part due to the heterogeneity in patient symptoms, trajectories and manifestations. There is a known genetic component of PD and genomic datasets have helped to uncover some aspects of the disease....

Topics

• Parkinson Disease
• Humans
• Longitudinal Studies
• Polymorphism, Single Nucleotide
• Disease Progression
• Computational Biology