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Article

Causal relationship between inflammatory proteins and attention deficit hyperactivity disorder: A serum-metabolites-mediated Mendelian randomization analysis.

Medicine - 29 May 2026

Zhou Kangning, Zhang Qiang, Liu Miaomiao, Yan Yurou, Wang Junhong

Abstract excerpt

Neuroinflammation is a potential pathogenesis of attention deficit hyperactivity disorder (ADHD). However, its consistency and specific causality remain unclear. We investigated the causal relationship between 91 inflammatory proteins and ADHD and explored the potential mediating role of 1400 serum metabolites. We obtained genome-wide association study (GWAS) data for 91 inflammatory proteins (n = 14,824), 1400...

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PMID: 42216364
DOI: 10.1097/MD.0000000000048963
PMCID: PMC13225583

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CD40

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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