Article
Phenotypic clustering identifies heterogeneous cardiovascular risk among patients with elevated lipoprotein(a).
Scientific reports - 28 May 2026
Joo Hyung Joon, Hong Soon Jun, Yu Cheol Woong, Shin Seung Yong, Kim Eung Ju
Abstract excerpt
Lipoprotein(a) [Lp(a)] is an established cardiovascular risk enhancer, yet fixed concentration thresholds may not fully capture the heterogeneity of cardiovascular risk among individuals with elevated levels. We retrospectively analyzed 17,653 patients with Lp(a) measurements from three tertiary hospitals (2017-2024). After exclusions, 2355 patients with Lp(a) ≥ 50 mg/dL underwent k-means clustering based on 23...
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