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Article

Liquid biopsy-based genomic risk score to predict neurologic death in non-small cell lung cancer patients.

Journal of neuro-oncology - 25 May 2026

Glynn Sarah E, D'Agostino Ralph, Lanier Claire M, R Choi Ariel, Farris Michael, Abdulhaleem Mohammed, Young Patrick, Wang Yuezhu, Smith Margaret, Ruiz Jimmy, Lycan Thomas, Petty William Jeffrey, Cramer Christina K, Tatter Stephen B, Laxton Adrian W, White Jaclyn J, Su Jing, T Whitlow Christopher, Xing Fei, Chan Michael D, Helis Corbin A

Abstract excerpt

INTRODUCTION: Biomarkers that predict neurologic death may allow for personalization of therapy for high-risk brain metastases patients. METHODS: Patients with NSCLC who underwent comprehensive genomic profiling were identified in an institutional database. Neurologic death was determined by medical record review. Proportional hazards regression models considering non-neurologic death as a competing risk were...

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Identifiers

PMID: 42185640
DOI: 10.1007/s11060-026-05642-z
PMCID: PMC13201357

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