Classical HLA class II associations with ALS in Kuwait reveal a DR7-DQ2.2 risk haplotype.

doi:10.3389/fimmu.2026.1820694

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Classical HLA class II associations with ALS in Kuwait reveal a DR7-DQ2.2 risk haplotype.

Frontiers in immunology - 1 Jan 2026

Dashti Mohammed, AlAbdulghafour Faye, AlMutairi Ohood, Mohammad Anwar, Malik Md Zubbair, AlRefaie Khadeja, Nizam Rasheeba, Jacob Sindhu, Chalabi Ammar, Al Khleifat Ahmad, Al-Mulla Fahd

Abstract excerpt

Background: Genome-wide association studies have implicated the human leukocyte antigen/major histocompatibility complex (HLA/MHC) region in amyotrophic lateral sclerosis (ALS) susceptibility, and immune dysregulation is increasingly recognised as a modifier of disease course. High-resolution HLA data for ALS remain confined to European and East Asian ancestries. We tested whether classical HLA class I and class...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Amyotrophic Lateral Sclerosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Genome-Wide Association Study

Share to Haplotypes

Share to Histocompatibility Antigens Class II

Share to HLA-DQ Antigens

Share to Kuwait

Source

Open in PubMed Open full text

Identifiers

PMID: 42183197
DOI: 10.3389/fimmu.2026.1820694
PMCID: PMC13194005

Provenance

PubMed metadata and Literature Corpus relationships.