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Article

PPARA Gene Polymorphisms and Their Association with COPD in Tibetan and Han Populations from Gansu, China.

International journal of chronic obstructive pulmonary disease - 1 Jan 2026

Gao Renjie, Zhang Miao, Zhang Yangjie, Wang Yunchao, Yang Zhen, Lin Ao, Wu Yanlin, Wang Xinhua

Abstract excerpt

Background: Chronic Obstructive Pulmonary Disease (COPD) is influenced by both genetic and environmental factors, with chronic hypoxia playing a pivotal role in its pathogenesis. Peroxisome proliferator-activated receptor alpha (PPARA), a core regulator of the hypoxia pathway, exhibits genetic differentiation in high-altitude populations. This study aimed to investigate the association between PPARA gene...

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Identifiers

PMID: 42180800
DOI: 10.2147/COPD.S590361
PMCID: PMC13191043

Genes

PPARA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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