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Article

A simple model captures key characteristics of biological non-deterministic genotype-phenotype maps.

PLoS computational biology - 1 May 2026

Martin Nora S

Abstract excerpt

By connecting genotypic mutations to the higher-level phenotypes relevant for selection, genotype-phenotype (GP) maps play a key role in evolution. GP maps are typically investigated using computational models of biophysical phenotypes (for example, RNA secondary structures and simplified models of protein tertiary and quaternary structures), but GP map concepts are relevant beyond these specific models. While...

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Identifiers

PMID: 42172291
DOI: 10.1371/journal.pcbi.1014272
PMCID: PMC13196979

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