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Article

Toward personalized medicine in childhood nephrotic syndrome.

Kidney international - 1 Jun 2026

Chan Eugene Yu-Hin, Boyer Olivia

Abstract excerpt

Childhood idiopathic nephrotic syndrome remains treated empirically despite profound pathophysiological heterogeneity. Tu et al. develop a polygenic risk score incorporating clinical data and human leukocyte antigen class II variants to stratify steroid responsiveness at diagnosis. Although predictive performance remains modest and several limitations preclude immediate clinical translation, this work represents...

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Identifiers

PMID: 42167867
DOI: 10.1016/j.kint.2026.04.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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