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Article

Genetic determinants of drug-induced gingival overgrowth.

Scientific reports - 20 May 2026

Kiattiubolwong Thunchanok, Nakhonsri Vorthunju, Katanyuwong Kamornwan, Jaihan Thippawan, Klinhom Chamaiporn, Ngamphiw Chumpol, Wasitthankasem Rujipat, Herzberg Mark C, Tongsima Sissades, Kantaputra Piranit Nik

Abstract excerpt

Drug-induced gingival overgrowth (DIGO) is a multifactorial adverse effect associated with calcium channel blockers and antiepileptic drugs, yet genetic susceptibility-particularly in Asian populations-remains poorly defined. We performed whole-genome sequencing in 74 Thai individuals, including 36 DIGO cases and 38 drug-exposed nonresponder controls. A genome-wide association study was conducted with adjustment...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42156840
DOI: 10.1038/s41598-026-52779-y
PMCID: PMC13388721

Genes

BBS1
C1QL2
CYP2C9
RWDD1
TOM1L1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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