Article
Genetic Susceptibility to Periodontal Disease in Down Syndrome: A Case-Control Study.
International journal of molecular sciences - 10 Jun 2021
Fernández María, de Coo Alicia, Quintela Inés, García Eliane, Diniz-Freitas Márcio, Limeres Jacobo, Diz Pedro, Blanco Juan, Carracedo Ángel, Cruz Raquel
Abstract excerpt
Severe periodontitis is prevalent in Down syndrome (DS). This study aimed to identify genetic variations associated with periodontitis in individuals with DS. The study group was distributed into DS patients with periodontitis (n = 50) and DS patients with healthy periodontium (n = 36). All samples were genotyped with the "Axiom Spanish Biobank" array, which contains 757,836 markers. An association analysis at...
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