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Article

Genetically Supported Drug Targets and Dental Traits: A Mendelian Randomization Study.

Journal of dental research - 1 Nov 2024

Liu L, Wang T, Duan C, Mao S, Wu B, Chen Y, Huang D, Cao Y

Abstract excerpt

Current interventions for oral/dental diseases heavily rely on operative/surgical procedures, while the discovery of novel drug targets may enable access to noninvasive pharmacotherapy. Therefore, this study aims to leverage large-scale data and Mendelian randomization (MR) techniques, utilizing genetic variants as instruments, to identify potential therapeutic targets for oral and dental diseases supported by...

Topics

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CXCL10 gene
TNF gene
Genome-Wide Association Study
Mendelian Randomization Analysis
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Quantitative Trait Loci

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Open in PubMed Open full text

Identifiers

PMID: 39370703
DOI: 10.1177/00220345241272045
PMCID: PMC11653268

Genes

CXCL10
IL12RB1
TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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